GPR75-H41D

Family :

membrane protein

Catalog No. :

GPR75-H41D

Protein :

GPR75

UniProt :

O95800

Organism :

Homo sapiens

Expression system :

Mammalian cell

Tag :

eGFP, 10His

Sequence :

Inquire for more details

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  GPR75

Alias:  Probable G-protein coupled receptor 75

Uniprot: O95800

Background: G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Construct: HA(signal peptide)-Flag-GPR75(M1-V540 end)-3C-eGFP-10His

Expression Host: Mammalian

Purity: 60%

Formulation: 20 mM HEPES pH 7.5, 200 mM NaCl, 1.5% glycerol, 5 mM EDTA, 0.01% (w/v)LMNG, and 0.001% (w/v)CHS

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.