Catalog No. ：
Expression system ：
Symbol/Gene Name: APLNR
Alias: Apelin receptor,Angiotensin receptor-like 1,G-protein coupled receptor APJ,G-protein coupled receptor HG11
Background: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753, PubMed:28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed:25639753, PubMed:28137936).
Construct: Flag-BRIL-3C-APJ(M1-R330) (T177N, C325L, C326M)-10His
Expression Host: Insect cell
Formulation: 25 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 0.01% (w/v) DDM, 0.002% (w/v) CHS
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.