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UniProt :


Organism :

Homo sapiens

Expression system :

Insect cell

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Product Information

Symbol/Gene Name:  APLNR

Alias:  Apelin receptor,Angiotensin receptor-like 1,G-protein coupled receptor APJ,G-protein coupled receptor HG11

Uniprot: P35414

Background: Receptor for apelin receptor early endogenous ligand (APELA) and apelin (APLN) hormones coupled to G proteins that inhibit adenylate cyclase activity (PubMed:11090199, PubMed:25639753, PubMed:28137936). Plays a key role in early development such as gastrulation, blood vessels formation and heart morphogenesis by acting as a receptor for APELA hormone (By similarity). May promote angioblast migration toward the embryonic midline, i.e. the position of the future vessel formation, during vasculogenesis (By similarity). Promotes sinus venosus (SV)-derived endothelial cells migration into the developing heart to promote coronary blood vessel development (By similarity). Plays also a role in various processes in adults such as regulation of blood vessel formation, blood pressure, heart contractility and heart failure (PubMed:25639753, PubMed:28137936).

Construct: Flag-BRIL-3C-APJ(M1-R330) (T177N, C325L, C326M)-10His

Expression Host: Insect cell

Purity: 85%

Formulation: 25 mM HEPES pH 7.5, 500 mM NaCl, 5% glycerol, 0.01% (w/v) DDM, 0.002% (w/v) CHS

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.


< 0.01 EU per μg of the protein


Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.