ATG9B-H04A

Family :

Apoptosis

Catalog No. :

ATG9B-H04A

Protein :

ATG9B

UniProt :

Q674R7

Organism :

Homo sapiens

Expression system :

Mammalian cell

Tag :

Flag

Sequence :

M1-D924

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  ATG9B

Alias:  Autophagy-related protein 9B,APG9-like 2,Nitric oxide synthase 3-overlapping antisense gene protein,Protein sONE

Uniprot: Q674R7

Background: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). In addition to autophagy, also plays a role in necrotic cell death (By similarity).

Construct: ATG9B(M1-D924 end)-Flag

Expression Host: Mammalian cells

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.