Catalog No. ：
Expression system ：
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Symbol/Gene Name: GRM5
Alias: Metabotropic glutamate receptor 5,mGluR5
Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Construct: GRM5(P569-K678) (E579A, N667Y, I669A, G675M)-T4L-GRM5(K679-A836) (T742A, S753A)-10His
Expression Host: Insect cell
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.