BACH2-H13A

Family :

E3 ubiquitin-protein ligase

Catalog No. :

BACH2-H13A

Protein :

BACH2

UniProt :

Q9BYV9

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

His/Strep

Sequence :

S2-T841

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  BACH2

Alias:  Transcription regulator protein BACH2,BTB and CNC homolog 2

Uniprot: Q9BYV9

Background: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation (PubMed:28530713).

Construct: 8His-StrepII-TEV-(GG)-BACH2(S2-T841 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.