Family :


Catalog No. :


Protein :


UniProt :


Organism :

Homo sapiens

Expression system :

Insect cell

Tag :


Sequence :


Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  CAMK2A

Alias:  Calcium/calmodulin-dependent protein kinase type II subunit alpha,CaM kinase II subunit alpha,CaMK-II subunit alpha

Uniprot: Q9UQM7

Background: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (By similarity). Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378). Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity (By similarity).

Construct: GST-TEV-GG-CaMK2α(A2-H478 end)

Expression Host: Insect cell

Purity: 85%

Formulation: 50 mM Tris-HCl (pH 7.5), 150 mM NaCl, 5% glycerol, 5mM DTT, 0.1M Trehalose

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.


< 0.01 EU per μg of the protein


Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.