PIP4K2C-H01A

Family :

Kinase

Catalog No. :

PIP4K2C-H01A

Protein :

PIP4K2C

UniProt :

Q8TBX8

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

A2-A421

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  PIP4K2C

Alias:  Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma,Phosphatidylinositol 5-phosphate 4-kinase type II gamma,PI(5)P 4-kinase type II gamma,PIP4KII-gamma

Uniprot: Q8TBX8

Background: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3 (PubMed:31091439).

Construct: 6His-TEV-GG-PIP4K2C(A2-A421 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.