E3 ubiquitin-protein ligase
Catalog No. ：
Expression system ：
Symbol/Gene Name: PPIL2
Alias: RING-type E3 ubiquitin-protein ligase PPIL2,CYC4,Cyclophilin-60,Cyclophilin-like protein Cyp-60,Cyp60,hCyP-60,Probable inactive peptidyl-prolyl cis-trans isomerase-like 2,PPIase,Rotamase PPIL2
Background: Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423). May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance (PubMed:15946952). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).
Construct: (GG)-PPIL2(G2-W520 end)
Expression Host: E. coli
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.