PPIL2-H01A

Family :

E3 ubiquitin-protein ligase

Catalog No. :

PPIL2-H01A

Protein :

PPIL2

UniProt :

Q13356

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

G2-W520

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  PPIL2

Alias:  RING-type E3 ubiquitin-protein ligase PPIL2,CYC4,Cyclophilin-60,Cyclophilin-like protein Cyp-60,Cyp60,hCyP-60,Probable inactive peptidyl-prolyl cis-trans isomerase-like 2,PPIase,Rotamase PPIL2

Uniprot: Q13356

Background: Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423). May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance (PubMed:15946952). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PubMed:20676357).

Construct: 6His-TEV-(GG)-PPIL2(G2-W520 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.