CDK15/Cyclin Y-H00A

Family :

CDK

Catalog No. :

CDK15/Cyclin Y-H00A

Protein :

CDK15/Cyclin Y

UniProt :

Q96Q40/Q8ND76

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

No tag

Sequence :

M1-W435/M1-S341

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  CDK15;CCNY

Alias:  Cyclin-dependent kinase 15,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein,Cell division protein kinase 15,Serine/threonine-protein kinase ALS2CR7,Serine/threonine-protein kinase PFTAIRE-2;Cyclin-Y,Cyc-Y,Cyclin box protein 1,Cyclin fold protein 1,cyclin-X

Uniprot: Q96Q40/Q8ND76

Background: Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
;
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

Construct: CDK15(1-435end)/Cyclin Y(1-341end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.