PYHIN1-H04B
Family ：
PRRs
Catalog No. ：
PYHIN1-H04B
Protein ：
PYHIN1
UniProt ：
Q6K0P9
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
Flag
Sequence ：
M1-P492
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: PYHIN1
Alias: Pyrin and HIN domain-containing protein 1,Interferon-inducible protein X
Uniprot: Q6K0P9
Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Construct: PYHIN1(M1-P492 end)-Flag
Expression Host: E.Coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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