RdRp-O13C

Family :

Virus Protein

Catalog No. :

RdRp-O13C

Protein :

RdRP

UniProt :

G7WZE3

Organism :

Influenza A virus

Expression system :

Insect cell

Tag :

His/Strep

Sequence :

M1-R716

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  PA

Alias:  Polymerase acidic protein,RNA-directed RNA polymerase subunit P2

Uniprot: G7WZE3

Background: Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.

Construct: 8His-Strep-TEV-RdRp(M1-R716 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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