CYP2E1-H00A

Family :

Cytochrome c/b and P450

Catalog No. :

CYP2E1-H00A

Protein :

CYP2E1

UniProt :

P05181

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

No tag

Sequence :

L32-S493

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  CYP2E1

Alias:  Cytochrome P450 2E1,4-nitrophenol 2-hydroxylase,CYPIIE1,Cytochrome P450-J

Uniprot: P05181

Background: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed:10553002, PubMed:18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:10553002, PubMed:18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed:10553002, PubMed:18577768). May be involved in the oxidative metabolism of xenobiotics (Probable).

Construct: MAKKTSSKGK-CYP2E1(32-493)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.