CYP2E1-H01A
Family ：
Cytochrome c/b and P450
Catalog No. ：
CYP2E1-H01A
Protein ：
CYP2E1
UniProt ：
P05181
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
His
Sequence ：
L32-S493
Assay ：
Structure ：
Inquiry ：
是
Product Information
Symbol/Gene Name: CYP2E1
Alias: Cytochrome P450 2E1,4-nitrophenol 2-hydroxylase,CYPIIE1,Cytochrome P450-J
Uniprot: P05181
Background: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed:10553002, PubMed:18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:10553002, PubMed:18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed:10553002, PubMed:18577768). May be involved in the oxidative metabolism of xenobiotics (Probable).
Construct: MAKKTSSKGK-CYP2E1(32-493)-TEV-6His
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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