Family :

Kinase

Catalog No. :

DCK-H00A

Protein :

DCK

UniProt :

P27707

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

No tag

Sequence :

M1-L260

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  DCK

Alias:  Deoxycytidine kinase,dCK,Deoxyadenosine kinase,Deoxyguanosine kinase

Uniprot: P27707

Background: Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine (PubMed:1996353, PubMed:12808445, PubMed:18377927, PubMed:19159229, PubMed:20614893). Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents (PubMed:12808445).

Construct: GG-DCK(M1-L260 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.