BP09508-13A

Family :

CD antigen and immunoglobulin receptor

Catalog No. :

BP09508-13A

Protein :

DC-SIGN

UniProt :

Q9NNX6

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His/Strep,Flag

Sequence :

M1-A404

Inquiry :

Product Information

Symbol/Gene Name:  CD209

Alias:  CD209 antigen,C-type lectin domain family 4 member L,Dendritic cell-specific ICAM-3-grabbing non-integrin 1,DC-SIGN,DC-SIGN1,CD209

Uniprot: Q9NNX6

Background: Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

Construct: 6His-StrepII-TEV-DC-SIGN(M1-A404 end)-Flag

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

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