SERCA2b-H13A
Family :
membrane protein
Catalog No. :
SERCA2b-H13A
Protein :
SERCA2b
UniProt :
P16615
Organism :
Homo sapiens
Expression system :
Mammalian cell
Tag :
Strep II/His
Sequence :
Inquire for more details
Assay :
Structure :
Inquiry :
是
Symbol/Gene Name: ATP2A2
Alias: Sarcoplasmic/endoplasmic reticulum calcium ATPase 2,SERCA2,SR Ca(2+)-ATPase 2,Calcium pump 2,Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase
Uniprot: P16615
Background: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:16402920). Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation (PubMed:28890335). Also modulates ER contacts with lipid droplets, mitochondria and endosomes (PubMed:28890335).
Construct: 10His-Strep II-eGFP-SERCA2b(M1-S1042 end)
Expression Host: Mammalian
Purity: 85%
Formulation:
Supplied as sterile 50 mM HEPES pH 7.5, 100 mM KCl , 1mM DTT, 1mM CaCl2, 1mM MgCl2, 0.001% (w/v) LMNG
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein