BP18820-13A

Family :

membrane protein

Catalog No. :

BP18820-13A

Protein :

SERCA2b

UniProt :

P16615

Organism :

Homo sapiens

Expression system :

Mammalian cell

Tag :

Strep II/His

Sequence :

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Inquiry :

Symbol/Gene Name:  ATP2A2

Alias:  Sarcoplasmic/endoplasmic reticulum calcium ATPase 2,SERCA2,SR Ca(2+)-ATPase 2,Calcium pump 2,Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca(2+) ATPase

Uniprot: P16615

Background: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (PubMed:16402920). Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation (PubMed:28890335). Also modulates ER contacts with lipid droplets, mitochondria and endosomes (PubMed:28890335).

Construct: 10His-Strep II-eGFP-SERCA2b(M1-S1042 end)

Expression Host: Mammalian

Purity: 85%

Formulation:

Supplied as sterile 50 mM HEPES pH 7.5, 100 mM KCl , 1mM DTT, 1mM CaCl2, 1mM MgCl2, 0.001% (w/v) LMNG

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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