DTX3-H02B

Family :

E3 ubiquitin-protein ligase

Catalog No. :

DTX3-H02B

Protein :

DTX3

UniProt :

Q8N9I9

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

GST

Sequence :

S2-D347

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  DTX3

Alias:  Probable E3 ubiquitin-protein ligase DTX3,Protein deltex-3,Deltex3,RING finger protein 154,RING-type E3 ubiquitin transferase DTX3

Uniprot: Q8N9I9

Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context (By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Construct: GST-TEV-(GG)-DTX3(S2-D347 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.