KLHL21-H13A
Family ：
E3 ubiquitin-protein ligase
Catalog No. ：
KLHL21-H13A
Protein ：
KLHL21
UniProt ：
Q9UJP4
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
His/Strep
Sequence ：
E2-H597
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: KLHL21
Alias: Kelch-like protein 21
Uniprot: Q9UJP4
Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
Construct: 8His-StrepII-TEV-(GG)-KLHL21(E2-H597 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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