ERK3-H01A

Family :

Kinase

Catalog No. :

ERK3-H01A

Protein :

ERK3

UniProt :

Q16659

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

M9-I327

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  MAPK6

Alias:  Mitogen-activated protein kinase 6,MAP kinase 6,MAPK 6,Extracellular signal-regulated kinase 3,ERK-3,MAP kinase isoform p97,p97-MAPK

Uniprot: Q16659

Background: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).

Construct: 6His-TEV-S-ERK3(M9-I327) (L290V)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.