KMT2D-H02B
Family ：
E3 ubiquitin-protein ligase
Catalog No. ：
KMT2D-H02B
Protein ：
KMT2D
UniProt ：
O14686
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
GST
Sequence ：
H5382-M5536
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: KMT2D
Alias: Histone-lysine N-methyltransferase 2D,Lysine N-methyltransferase 2D,ALL1-related protein,Myeloid/lymphoid or mixed-lineage leukemia protein 2
Uniprot: O14686
Background: Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) (PubMed:25561738). Part of chromatin remodeling machinery predominantly forms H3K4me1 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:17500065). Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription (PubMed:16603732).
Construct: GST-TEV-(GG)-KMT2D(H5382-M5536)
Expression Host: E. coli
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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