Protease and Enzyme
Catalog No. ：
Expression system ：
Symbol/Gene Name: FNTA
Alias: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,CAAX farnesyltransferase subunit alpha,FTase-alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha,GGTase-I-alpha
Background: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.
Construct: 6His-strepII-TEV-GG-FNTA(M1-Q379 end)
Expression Host: E. coli
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.