Catalog No. ：
Expression system ：
Symbol/Gene Name: CDK15;CCNY
Alias: Cyclin-dependent kinase 15,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein,Cell division protein kinase 15,Serine/threonine-protein kinase ALS2CR7,Serine/threonine-protein kinase PFTAIRE-2;Cyclin-Y,Cyc-Y,Cyclin box protein 1,Cyclin fold protein 1,cyclin-X
Background: Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Construct: N-GST-3C-CDK15(1-435end)/pFastBac1-N-Flag-3C-Cyclin Y(1-341end)
Expression Host: Insect cell
Supplied as sterile 25 mM HEPES (pH 7.5), 500 mM NaCl, 5% glycerol, 1 mM DTT, 20 mM GSH.
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.