UBA6-H00A
Family :
E1 ubiquitin-activating enzyme
Catalog No. :
UBA6-H00A
Protein :
UBA6
UniProt :
A0AVT1
Organism :
Homo sapiens
Expression system :
Insect cell
Tag :
No tag
Sequence :
E2-D1052
Assay :
Structure :
Inquiry :
是
Symbol/Gene Name: UBA6
Alias: Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-activating enzyme 6,Monocyte protein 4,MOP-4,Ubiquitin-activating enzyme E1-like protein 2,E1-L2
Uniprot: A0AVT1
Background: Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
Construct: (GG)-UBA6(E2-D1052 end)
Expression Host: Insect cell
Purity: 85%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 5% glycerol, 1 mM DTT.
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein