USP6-H02A
Family ：
DUBs
Catalog No. ：
USP6-H02A
Protein ：
USP6
UniProt ：
P35125
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
GST
Sequence ：
K529-Q1406
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: USP6
Alias: Ubiquitin carboxyl-terminal hydrolase 6,Deubiquitinating enzyme 6,Proto-oncogene TRE-2,Ubiquitin thioesterase 6,Ubiquitin-specific-processing protease 6
Uniprot: P35125
Background: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Construct: GST-TEV-GG-USP6(K529-Q1406 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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