USP21-H02B
Family ：
DUBs
Catalog No. ：
USP21-H02B
Protein ：
USP21
UniProt ：
Q9UK80
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
GST
Sequence ：
P2-L565
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: USP21
Alias: Ubiquitin carboxyl-terminal hydrolase 21,Deubiquitinating enzyme 21,Ubiquitin thioesterase 21,Ubiquitin-specific-processing protease 21
Uniprot: Q9UK80
Background: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di- and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity). Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates (PubMed:10799498). Deubiquitinates BAZ2A/TIP5 leading to its stabilization (PubMed:26100909).
Construct: GST-TEV-GG-USP21(P2-L565 end)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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