USP46-H00B

Family :

DUBs

Catalog No. :

USP46-H00B

Protein :

USP46

UniProt :

P62068

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

No tag

Sequence :

M1-E366

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  USP46

Alias:  Ubiquitin carboxyl-terminal hydrolase 46,Deubiquitinating enzyme 46,Ubiquitin thioesterase 46,Ubiquitin-specific-processing protease 46

Uniprot: P62068

Background: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).

Construct: USP46(M1-E366 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.