USP46-H12B
Family ：
DUBs
Catalog No. ：
USP46-H12B
Protein ：
USP46
UniProt ：
P62068
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
His/GST
Sequence ：
M1-E366
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: USP46
Alias: Ubiquitin carboxyl-terminal hydrolase 46,Deubiquitinating enzyme 46,Ubiquitin thioesterase 46,Ubiquitin-specific-processing protease 46
Uniprot: P62068
Background: Deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. May act by mediating the deubiquitination of GAD1/GAD67 (By similarity). Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity (PubMed:19075014, PubMed:26388029). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).
Construct: 6His-GST-TEV-USP46(M1-E366 end)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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