IL-4-H01A

Family :

Cytokine/recepter and gowth factor

Catalog No. :

IL-4-H01A

Protein :

IL-4

UniProt :

P05112

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

H25-S153

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  IL4

Alias:  Interleukin-4,IL-4,B-cell stimulatory factor 1,BSF-1,Binetrakin,Lymphocyte stimulatory factor 1,Pitrakinra

Uniprot: P05112

Background: Participates in at least several B-cell activation processes as well as of other cell types (PubMed:3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages (By similarity). Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4 (By similarity).

Construct: 6His-TEV-GG-IL-4(H25-S153 end)

Expression Host: E. coli

Purity: 80%

Formulation: 25 mM Tris-HCl (pH 8.0), 100 mM NaCl.

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.