JMJD2C-H01A

Family :

Epigenetic

Catalog No. :

JMJD2C-H01A

Protein :

JMJD2C

UniProt :

Q9H3R0

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

M1-K347

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  KDM4C

Alias:  Lysine-specific demethylase 4C,Gene amplified in squamous cell carcinoma 1 protein,GASC-1 protein,JmjC domain-containing histone demethylation protein 3C,Jumonji domain-containing protein 2C,[histone H3]-trimethyl-L-lysine(9) demethylase 4C

Uniprot: Q9H3R0

Background: Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.

Construct: 6His-TEV-JMJD2C(M1-K347)

Expression Host: E. coli

Purity:  90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.