Family :

GPCR

Catalog No. :

MT1-H41A

Protein :

MT1

UniProt :

P48039

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

His / Flag

Sequence :

S12-N325

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  MTNR1A

Alias:  Melatonin receptor type 1A,Mel-1A-R,Mel1a receptor

Uniprot: P48039

Background: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Construct: Flag-8His-TEV-MT1(S12-N325, with 219-227 be replaced by PGS, D73N, L95F, G104A, F116W, N124D, C127L, W251F, A292P, N299D)

Expression Host: Insect cell

Purity: 60%

Formulation: 50 mM HEPES (pH 7.5), 500 mM NaCl, 10% glycerol, 0.025% DDM, 100 uM Ramelteon

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.