SLC1A3-H154B

Family :

SLC

Catalog No. :

SLC1A3-H154B

Protein :

SLC1A3

UniProt :

P43003

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-MBP,Flag

Sequence :

T2-M542

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SLC1A3

Alias:  Excitatory amino acid transporter 1,Sodium-dependent glutamate/aspartate transporter 1,GLAST-1,Solute carrier family 1 member 3

Uniprot: P43003

Background: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7521911, PubMed:8123008, PubMed:20477940, PubMed:26690923, PubMed:28032905, PubMed:28424515). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:20477940). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:20477940). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).

Construct: 8His-MBP-TEV-(GG)-SLC1A3(T2-M542)-Flag

Expression Host: Insect cell

Purity: 80%

Formulation:

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.