SLC11A1-H154B
Family ：
SLC
Catalog No. ：
SLC11A1-H154B
Protein ：
SLC11A1
UniProt ：
P49279
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
8His-MBP,Flag
Sequence ：
T2-G550
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: SLC11A1
Alias: Natural resistance-associated macrophage protein 1,NRAMP 1,Solute carrier family 11 member 1
Uniprot: P49279
Background: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.
Construct: 8His-MBP-TEV-(GG)-SLC11A1(T2-G550)-Flag
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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