SLC11A2-H154B

Family :

SLC

Catalog No. :

SLC11A2-H154B

Protein :

SLC11A2

UniProt :

P49281

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-MBP,Flag

Sequence :

V2-R568

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SLC11A2

Alias:  Natural resistance-associated macrophage protein 2,NRAMP 2,Divalent cation transporter 1,Divalent metal transporter 1,DMT-1,Solute carrier family 11 member 2

Uniprot: P49281

Background: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

Construct: 8His-MBP-TEV-(GG)-SLC11A2(V2-R568)-Flag

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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