NLRP5-H135A
Family ：
PRRs
Catalog No. ：
NLRP5-H135A
Protein ：
NLRP5
UniProt ：
P59047
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
His/Strep/MBP
Sequence ：
G227-N1200
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: NLRP5
Alias: NACHT, LRR and PYD domains-containing protein 5, Mater protein homolog, Maternal Antigen that Embryos Require
Uniprot: P59047
Background: As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity). Required for the formation of F-actin cytoplasmic lattices (CPL) in oocytes, which in turn are responsible for symmetric division of zygotes via the regulation of mitotic spindle formation and positioning (By similarity). Required for the localization of cortical granules to the cortex of oocytes, via association with the cortical actin scaffold (By similarity). Required for cortical actin clearance prior to oocyte exocytosis (By similarity). Involved in regulating post-fertilization Ca(2+) release and endoplasmic reticulum (ER) storage via regulation of ER localization (By similarity). May be involved in the localization of mitochondria to the cytoplasm and perinuclear region in oocytes and early stage embryos, independent of its role in CPL formation (By similarity).
Construct: 8His-strepII-MBP-TEV-NLRP5(G227-N1200 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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