NOSIP-H00A
Family ：
E3 ubiquitin-protein ligase
Catalog No. ：
NOSIP-H00A
Protein ：
NOSIP
UniProt ：
Q9Y314
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
No tag
Sequence ：
T2-A301
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: NOSIP
Alias: Nitric oxide synthase-interacting protein,E3 ubiquitin-protein ligase NOSIP,RING-type E3 ubiquitin transferase NOSIP,eNOS-interacting protein
Uniprot: Q9Y314
Background: E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB (By similarity). Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity (PubMed:11149895, PubMed:15548660, PubMed:16135813).
Construct: (GG)-NOSIP(T2-A301 end)
Expression Host: E. coli
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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