SLC15A2-H154B

Family :

SLC

Catalog No. :

SLC15A2-H154B

Protein :

SLC15A2

UniProt :

Q16348

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-MBP,Flag

Sequence :

N2-L729

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SLC15A2

Alias:  Solute carrier family 15 member 2,Kidney H(+)/peptide cotransporter,Oligopeptide transporter, kidney isoform,Peptide transporter 2

Uniprot: Q16348

Background: Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:7756356, PubMed:18367661). Transports the dipeptide-like aminopeptidase inhibitor bestatin (By similarity). Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity). Also able to transport carnosine (PubMed:31073693). Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs) (By similarity). Probably acts by mediating transport of bacterial peptidoglycans across the plasma membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).

Construct: 8His-MBP-TEV-(GG)-SLC15A2(N2-L729)-Flag

Expression Host: Insect cell

Purity: 90%

Formulation:

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.