SLC16A1-H134A

Family :

SLC

Catalog No. :

SLC16A1-H134A

Protein :

SLC16A1

UniProt :

P53985

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-Strep,Flag

Sequence :

P2-V500

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SLC16A1

Alias:  Monocarboxylate transporter 1,MCT 1,Solute carrier family 16 member 1

Uniprot: P53985

Background: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

Construct: 8His-Strep II-TEV-(GG)-SLC16A1(P2-V500)-Flag

Expression Host: Insect cell

Purity: 90%

Formulation:

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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