NSP5-H00A
Family ：
Virus Protein
Catalog No. ：
NSP5-H00A
Protein ：
NSP5
UniProt ：
P0C6U3
Organism ：
Human coronavirus HKU1
Expression system ：
E. coli
Tag ：
No tag
Sequence ：
S3335-V3634
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: 1a
Alias: Replicase polyprotein 1a,pp1a,ORF1a polyprotein
Uniprot: P0C6U3
Background: The papain-like proteinase 1 (PL1-PRO) and papain-like proteinase 2 (PL2-PRO) are responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PLP2 possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF-3 (By similarity).
Construct: (G)-AS-HKU1-NSP5(S3335-V3634)
Expression Host: E. coli
Purity: 90%
Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein
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