Protease and Enzyme
Catalog No. ：
Expression system ：
Symbol/Gene Name: patZ
Alias: Peptidyl-lysine N-acetyltransferase PatZ,Protein lysine acetyltransferase
Background: Catalyzes the acetyl-CoA-dependent acetylation of lysine residues of a large number of target proteins. Acetylates RNase R in exponential phase cells and RNase II (PubMed:21981926, PubMed:22124017, PubMed:26847092). Required for the glucose-dependent acetylation on multiple lysines of alpha, beta and beta' RNAP subunits (PubMed:21696463). Also acetylates acetyl-coenzyme A synthetase (Acs) and the chromosomal replication initiator protein DnaA, and inhibits their activity (PubMed:22059728, PubMed:26251518, PubMed:27484197). Overexpression leads to the acetylation of a large number of additional proteins and inhibits motility (PubMed:30352934).
Construct: 6His-StrepII-TEV-GG-patZ(S2-S886 end)
Expression Host: E. coli
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.