Sumo3-H01A

Family :

Others

Catalog No. :

Sumo3-H01A

Protein :

SUMO3

UniProt :

P55854

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

His

Sequence :

S2-F103

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SUMO3

Alias:  Small ubiquitin-related modifier 3,SUMO-3,SMT3 homolog 1,SUMO-2,Ubiquitin-like protein SMT3A,Smt3A

Uniprot: P55854

Background: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 (PubMed:11451954, PubMed:18538659, PubMed:21965678). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).

Construct: 6His-TEV-(GG)-Sumo3(S2-F103 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

 

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