GNAS/GNB1-H01A

Family :

GPCR

Catalog No. :

GNAS/GNB1-H01A

Protein :

G-Protein complex

UniProt :

P63092; P62873

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His

Sequence :

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Assay :

Structure :

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Symbol/Gene Name:  GNAS; GNB1

Alias:  Parathyroid hormone/parathyroid hormone-related peptide receptor,PTH/PTHrP type I receptor,PTH/PTHr receptor,Parathyroid hormone 1 receptor,PTH1 receptor

Uniprot: P63092; P62873

Background: This protein is produced by a bicistronic gene which also produces the ALEX protein from an overlapping reading frame.

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

Construct: GNAS(M1-L394 end) (S54N, G226A, E268A, N271K, K274D, R280K, T284D, I285T)/8His-TEV-GNB1(M1-N340 end)

Expression Host: Insect cell

Purity: 70%

Formulation: 10 mM HEPES pH 7.5, 100 mM NaCl, 10% glycerol, 1 mM MgCl2, 1 μM GDP, 0.1 mM TCEP

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.